Author

Qi-Chun Wei

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Open access Aug 2026

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

ABSTRACT Background and Aims Tumors actively remodel the tumor microenvironment (TME) to foster therapy resistance. However, the underlying mechanisms remain poorly defined. This study aims to characterize how colorectal cancer (CRC) cells drive TME remodeling to promote radioresistance. Methods A radioresistant CRC ce...

Yimin Fang, Jinglin Zhu, Qian Xiao et al. · Advancement of science · 0 citations

Review Open access Aug 2026

Cyclins and Cyclin‐Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer

This review critically evaluates recent mechanistic advances in CDK/cyclin biology and their pathological dysregulation across malignancies and highlights emerging approaches including proteolysis‐targeting chimeras, HSP90‐mediated targeting chimeras, hydrophobic tagging, molecular glues, and autophagy‐tethering compou...

Su-Ya Zheng, Zhi-Peng Shen, Yuan-Fang Wu et al. · MedComm · 0 citations