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Author

Qi Deng

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Review Open access Sep 2026

PIWIL4: from biological characteristics to disease pathogenesis and clinical applications

PIWIL4 is a core component of the PIWI/piRNA pathway. Its roles in germ cell development, transposon silencing, and genome stability maintenance are well established. Recent studies have shown that PIWIL4 is abnormally expressed in many cancers. There, it helps regulate key malignant processes—including cell cycle cont...

Qi Deng, Yi Liu, Yang Qu et al. · 0 citations
Review Open access Jul 2026

Early‐Onset Prostate Cancer: Epidemiology, Risk Factors, Biology, Clinical Features, Management, and Early Detection

Critically appraising the existing evidence, this work identifies key knowledge gaps, such as the understudied sporadic EOPC subgroup and the lack of dedicated clinical trials, and proposes future research directions to inform early detection and optimize therapeutic strategies for this unique patient population.

Xingyu Xiong, Wei Zhu, Weichao Huang et al. · 0 citations
Review Open access Jul 2026

Biological characteristics of ATP5A1 and its pathogenic mechanisms in human diseases: advances in clinical translation

This review establishes a comprehensive theoretical framework for understanding the role of ATP5A1 in disease pathogenesis and supports its potential utility in precision diagnostics and therapeutics.

Shu-Yin Yuan, Qi Deng, Hong-Juan Gao et al. · 0 citations

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