Motor dysfunction caused by neurological disorders such as stroke, spinal cord injury and amyotrophic lateral sclerosis has become a major global public health issue. Conventional rehabilitation approaches yield limited efficacy, highlighting the urgent need for innovative therapies. Brain-computer interface (BCI) tech...
Xiao-Ke Chai, Zhiyao Zheng, Nan Wang et al.· Stroke and vascular neurolog...· 0 citations
ABSTRACT Background Disorders of consciousness (DoC) lack an integrated framework to guide neuromodulation. This review updates three hierarchical frameworks—ARAS, mesocircuit, and ICNs—and maps therapeutic targets within each. Methods We synthesized recent neuroanatomical, optogenetic, neuroimaging, and clinical trial...