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Qi-Jia Wang

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Open access Jul 2026

LncPTEC mediated homocysteine accumulation elevates oxidative stress via UBQLN1-dependent MTHFD1 ubiquitination in DKD.

It is shown that homocysteine accumulation in proximal tubular epithelial cells (PTECs) is a significant contributor to mitochondrial oxidative stress in DKD and the role of the lncPTEC/MTHFD1 axis in Hcy-mediated mitochondrial oxidative stress is elucidated, offering potential diagnostic biomarkers and therapeutic tar...

Qi-Jia Wang, Tian-Hui Wu, Peilin Li et al. · 0 citations

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