Author

Qi-Jun Xie

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Review Open access Oct 2026

Rational Design and Delivery of Engineered Peptides: Toward a Unified Framework for Structure, Screening, and Application

This review presents a three-tiered engineering framework that systematically addresses these barriers. First, we survey chemical and sequence-based stabilization strategies, including lipidation, backbone N-methylation, and cyclization, that convert labile natural peptides into protease-resistant scaffolds. Second, mo...

Qi-Jun Xie, Hai-Ying Ma, Biao Liu et al. · Biology · 0 citations

Review Open access Sep 2026

Mitochondrial Remodeling, Cytoskeletal Dynamics, and Translational Control During Drosophila Spermatid Elongation: An Integrative Review

Simple Summary Spermatogenesis in Drosophila melanogaster provides a powerful model for understanding how a round germ cell is transformed into a highly elongated and functional sperm cell. Previous studies have identified many factors involved in sperm tail elongation and individualization, but these processes are oft...

Yang Fang, Jia-Xin Yin, Li-Ping Chen et al. · Biology · 0 citations

Jul 2026

CG31200 depletion disrupts germ cell differentiation during Drosophila spermatogenesis.

It is reported that CG31200, a predicted serine protease-related protein in Drosophila, plays an essential role in spermatogenesis and is associated with mitochondrial dysfunction, oxidative stress, altered transcriptional states, and defective axoneme formation.

Yang Fang, Feng-Chao Zhang, Xiuling Zhang et al. · Insect Science · 0 citations