Open access
Oct 2026
Programmable histone acetylation enables reversible regulation of cellulase production in Myceliophthora thermophila.
Myceliophthora thermophila is a thermophilic filamentous fungus with great potential for biomass biorefining and industrial protein production. However, the locus-specific epigenetic regulation of the cellulolytic network in this fungus remains poorly understood. Here, we established a CRISPR/dCas9-p300 system that rec...
Yao Li, Xiu-Cai Zhao, Xin-Yu Yang et al.
· Microbiology Research · 0 citations