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Open access Sep 2026

Integrative network toxicology and transcriptomic analyses identify DCP1B and HAS2 as key prognostic biomarkers in formaldehyde-associated Wilms tumor

Background and objectives Wilms tumor, a common childhood malignancy, has been hypothesized to be associated with environmental factors such as formaldehyde exposure. As a potential endocrine disruptor with reported pro-proliferative effects, the molecular mechanism underlying the role of formaldehyde in Wilms tumor re...

Gui-Jun Li, Sheng Zhang, Li-Na Chang et al. · 0 citations
Open access Sep 2026

EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy

Purpose EIF1, an RNA-binding protein implicated in multiple diseases, remains poorly characterized in diabetic retinopathy (DR). This study therefore investigated EIF1 expression and function in an in vitro model of DR pathogenesis. Methods Human retinal pigment epithelial cells (ARPE-19) were exposed to 50 mM glucose...

Na Li, Qian Ma, Xin Fan et al. · 0 citations

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