SpaFactor: Lightweight Spatial Context-Aware Gene Program Modeling for Histology-to-Transcriptomics Inference
Spatial transcriptomics (ST) profiles gene expression within tissue architecture, but its cost and experimental complexity limit routine use. Predicting spatial expression from routinely available hematoxylin and eosin (HE) images therefore offers a scalable alternative. However, conventional methods often fit high-dim...
Shi-Ting Ruan, Xi-Tong Ling, Qi-Ming He et al.
· 0 citations