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Review Open access Sep 2026

Evolution, application and clinical significance of profiling chromatin interactions at a genome-wide scale.

Over the past few decades, chromatin biology has evolved from viewing chromatin as a static structural scaffold to decoding it as a dynamic, programmable regulatory landscape. At the heart of this transformation is the precise mapping of interactions between functional proteins and cognate DNA elements. Although high-t...

Qi Qian, Yan-Hui Xu, Lu-Lin Wei · 0 citations
Open access Sep 2026

m5C Reader ALYREF Promotes the Progression of Endometrial Cancer by Activating the XRCC6‐Mediated Wnt/β‐catenin Signaling Pathway

ABSTRACT 5‐Methylcytosine (m5C) is a vital RNA modification that regulates mRNA stability, splicing, and nuclear export. As a key m5C reader, ALYREF promotes tumorigenesis across various cancers; however, its precise role in endometrial cancer (EC) remains unknown. ALYREF expression and clinical significance in EC were...

Lin-Lin Hao, Jian Zhang, Qi Qian et al. · 0 citations

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