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Open access Oct 2026

Integrated Single-Cell and Transcriptomic Analysis Suggests a Cuproptosis-Related Phenotype and Potential Therapeutic Target in Acute Pancreatitis

Acute pancreatitis (AP) is an acute inflammatory disorder of the exocrine pancreas with limited therapies. Whether cuproptosis, a copper-dependent cell death pathway, contributes to AP pathogenesis remains unknown. We integrated single-cell transcriptomics (GSE279876), single-cell transcriptomics (GSE188819), and human...

Qing-Feng Xie, Mao-Qin He, Qi Wang et al. · 0 citations
Open access Oct 2026

Dietary Sanguinarine Enhances Antioxidant Capacity and Intestinal Barrier Function in Yellow-Feathered Broilers via Modulation of Microbiota-Associated Butyrate Signaling

Sanguinarine (SA), a bioactive benzophenanthridine alkaloid, has emerged as a potential alternative to antibiotic growth promoters; however, its effects on intestinal redox homeostasis and epithelial regeneration remain incompletely understood. This study investigated whether dietary SA could improve growth performance...

Xin Li, Chuan-Bin Chen, Li-Hua Li et al. · 0 citations

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