Qi-Yuan Zhu

Subvoxel quantitative susceptibility mapping reveals distinct susceptibility patterns and clinical associations of juxtacortical paramagnetic rims in multiple sclerosis.

BACKGROUND Juxtacortical paramagnetic rims (JPRs) have emerged as potential biomarkers of cortical pathology in multiple sclerosis (MS), yet their susceptibility characteristics and clinical significance remain unclear. OBJECTIVES To characterize the heterogeneity of cortical lesions (CLs), with a particular focus on...

Enlarged perivascular spaces are associated with more severe microstructural damage in white matter lesions among people with relapsing-remitting multiple sclerosis.

Glymphatic surrogate, choroid plexus remodeling, and exploratory brain network analysis in the post-acute phase of anti-NMDAR encephalitis: multimodal MRI evidence for cognitive associations and differential white matter mediation

Background Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis typically presents with acute neuroinflammation, and many patients often experience persistent cognitive impairment during the post-acute/recovery phase. While impaired cerebrospinal fluid (CSF)-related markers—including glymphatic function and cho...

NODDI-derived U-Fiber MRI Markers for Risk Stratification of Progression Independent of Relapse Activity in Relapsing-remitting Multiple Sclerosis.

Advanced diffusion MRI-derived U-fiber metrics may complement clinical measures for exploratory PIRA risk stratification in RRMS and warrant validation in independent multicenter cohorts.