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Qi-Yuan Zou

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Open access Sep 2026

Gut Microbiota, Inflammatory Bowel Disease and the Prioritization of Host Effector Genes: A Two-Sample Mendelian Randomization Study with Independent Replication, cis-eQTL Colocalization and Single-Cell Localization

Gut microbial dysbiosis is common in inflammatory bowel disease (IBD), but whether specific taxa are causal, and through which host genes, remains unclear. We integrated two-sample Mendelian randomization (MR), replication, cis-eQTL colocalization, and single-cell mapping to identify microbial taxa with genetically pre...

Qi-Yuan Zou, Jian-Yi Wang · 0 citations
Open access Aug 2026

MultiDMPcaller: a one-stop software for detection and visualization of differentially methylated positions and regions

Abstract Motivation Whole-genome bisulfite sequencing (WGBS/BS-Seq) is the gold standard for single-base resolution DNA methylome profiling. However, the diverse statistical models of existing computational methods lead to limited overlap between their results, highlighting the need for novel methods to detect differen...

Qiu-Yu Yuan, Hong-Yan Zhao, Zhi-Jun Zhang et al. · 0 citations

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