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Author

Qi Zhu

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2 papers indexed here

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Review Open access Oct 2026

Follicular development impairment in polyendocrine metabolic ovarian syndrome: multidimensional pathophysiological networks and frontier therapeutic targets

Polyendocrine metabolic ovarian syndrome (PMOS) is a prevalent endocrine-metabolic disorder characterised by follicular arrest, anovulation, and elevated androgen levels. This review transcends single-dimensional analyses of PMOS pathology from neuroendocrine or metabolic perspectives, proposing an integrated multi-lay...

Qiu-Cheng Jia, Shu-Li Zhang, Li-Xing Zhang et al. · 0 citations
Open access Sep 2026

Lipotoxicity-induced ER-mitochondrial hypercoupling activates the mtDNA-cGAS-STING-NF-κB axis to drive follicular arrest in metabolically compromised PCOS

Polycystic ovary syndrome (PCOS) represents a major cause of anovulatory infertility worldwide, yet the mechanistic nexus linking metabolic perturbations to follicular microenvironment deterioration remains elusive. This study uncovers a novel pathogenic axis wherein lipotoxicity in metabolically compromised PCOS (M-...

Ming-Rui Xue, Qi Zhu, Shu-Li Zhang et al. · 0 citations

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