Open access
Sep 2026
Notoginsenoside R1 attenuates high-altitude pulmonary edema by targeting the NRF2-RIPK3/MLKL axis to suppress necroptosis and inflammation
Nuclear factor erythroid 2-related factor 2 (NRF2) is crucial for cell survival during oxidative stress by regulating antioxidant genes, with its transcriptional activity influenced by nuclear localization. Analysis of high-throughput transcriptomic data from GSE260910 in the GEO database indicates that NRF2 and RI...
Cai-Xia Pei, Jun-Ling Liu, Nan Jia et al.
· Food Science and Human Welln... · 0 citations