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Open access Jan 2026

FAP as a Clinical Biomarker: FAP+ CAFs Orchestrate an Immunosuppressive Stem Cell Niche via the COL1A1/2‐CD44 Axis in Colon Cancer

Background Colon cancer (CC) remains a leading cause of cancer‐related mortality worldwide, driven largely by the complex interactions within the tumor microenvironment (TME). Fibroblast activation protein (FAP) is highly expressed in cancer‐associated fibroblasts (CAFs) and is associated with poor prognosis, yet its r...

Qian Ding, Qing-Yan Lu · 0 citations

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