From Machine Learning-Enhanced Proteomics to a Validated Diagnostic Model: A Pipeline for Breast Cancer Biomarker Discovery via Independent and Transcriptomic Corroboration
Early diagnosis of breast cancer (BC) remains challenging. The limited sensitivity and specificity of existing serum tumor markers for reliable clinical application highlight the need to develop a more accurate and efficient screening workflow. This study analyzed serum samples from 255 breast cancer patients and 300 h...