Qian-Lei Xu

Macrophage polarization in Sjögren’s syndrome: from mechanisms to therapeutic translation

Sjögren’s syndrome (SS) is a chronic systemic autoimmune disease characterized by damage to exocrine glands, and no effective treatment is currently available to reverse glandular fibrosis. As core effector cells of innate immunity, macrophages play a pivotal role in the dynamic imbalance of polarization states, which...