Characterization of the immune landscape at the maternal-fetal interface and the role of endogenous T cells in the pathogenesis of preeclampsia.
BACKGROUND Preeclampsia (PE) is a major cause of maternal and fetal mortality and morbidity worldwide. The roles and characteristics of immune cells in PE pathogenesis remain incompletely understood. METHODS We collected the basal decidua, placentas, fetal membranes and umbilical cord blood from PE patients and healt...