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Author

Qian Ma

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Open access Sep 2026

EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy

Purpose EIF1, an RNA-binding protein implicated in multiple diseases, remains poorly characterized in diabetic retinopathy (DR). This study therefore investigated EIF1 expression and function in an in vitro model of DR pathogenesis. Methods Human retinal pigment epithelial cells (ARPE-19) were exposed to 50 mM glucose...

Na Li, Qian Ma, Xin Fan et al. · 0 citations
Open access Sep 2026

Multilevel genomic, transcriptomic, and epidemiologic evidence linking diabetic retinopathy to Alzheimer disease

Genetic liability to DR is associated with an increased risk of AD and is accompanied by shared expression-mediated effects and convergent neurovascular-metabolic pathways, which support the possibility that DR may serve as a clinically accessible indicator of increased neurodegenerative vulnerability.

Jing Li, Qian Liu, Qian Ma et al. · 0 citations

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