Aug 2026
Cardiac ACY1 ameliorates pathological hypertrophy by suppressing β-catenin/TCF4 signaling.
The findings establish the ACY1/β-catenin/TCF4/TCF4/UCHL1 pathway as a fundamental mechanism in disease progression, thereby proposing the enhancement of ACY1 function as a rational and innovative strategy to treat pressure-overload heart failure.
Yangxian Chen, Qiong Lai, Shengai Ye et al.
· International Immunopharmaco... · 0 citations