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Qian-Qian Li

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Open access Sep 2026

High-Calorie Diet Aggravates Lipopolysaccharide-Induced Pulmonary Inflammation in Juvenile Mice: Association of Acetate-Mediated Macrophage Polarization with AMPK/YAP Signaling

Macrophage polarization is an important modulator of the progression, severity, and resolution of pediatric pneumonia. Acetate, a metabolite produced by the gut microbiota, serves as a key regulator of macrophage polarization. Evidence demonstrates that a high-calorie diet (HCD) lowers acetate levels, thereby aggravati...

F. Sun, Hui Liu, Shu-Xuan Li et al. · 0 citations

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