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Qian-Qian Wang

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Open access Sep 2026

Paeoniflorigenone triggers TRIM28 phosphorylation-dependent ferroptosis and immune activation to suppress intrahepatic cholangiocarcinoma.

A previously unrecognized ferroptosis regulatory pathway is unveiled-the TRIM28/H3K9me3/HMOX1 axis-and it is demonstrated that PFG may represent a potential natural small-molecule candidate for ICC treatment.

Kai-Nan Lin, Yun-Kun Lu, Zhi-Hao Lin et al. · 0 citations

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