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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Qian-Qian Yao

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2 papers indexed here

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Open access 2026

Monitoring Molecular Residual Disease in Colorectal Cancer Using Tumor-Informed ctDNA Analysis

: Background: The early detection of molecular residual disease (MRD) is critical for predicting recurrence and guiding management in colorectal cancer (CRC). We aimed to evaluate the performance of tumor-informed circulating tumor DNA (ctDNA) analysis in monitoring MRD after curative-intent surgery. Methods: In this c...

William C. Cho, Yingyu Wang, Qian-Qian Yao et al. · 0 citations
Open access Sep 2026

MED24 deficiency promotes R-loop accumulation and sensitizes to SN-38 in triple-negative breast cancer

The application of DNA topoisomerase I (TOP1) inhibitors in triple-negative breast cancer (TNBC) still needs to be optimized. The principle of synthetic lethality represents a promising strategy to optimize TNBC treatment using SN-38, a representative TOP1 inhibitor and the active metabolite of irinotecan. MED24, yet...

Tao Shen, Xin-Hua Liu, Pei Huang et al. · 0 citations

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