Qian-Qiong Qin

The postsynaptic scaffold protein ABLIM1 regulates seizure susceptibility by maintaining GluA2 membrane localization in chronic epilepsy.

Temporal lobe epilepsy (TLE), the most common form of drug-resistant epilepsy (DRE) in adults, is a frequent chronic neurological disorder. Nevertheless, the precise pathophysiological mechanisms underlying TLE remain largely undefined. Our findings demonstrate that Actin-binding LIM protein 1 (ABLIM1) is broadly expre...