Pairing GOx With a Potent H2O2-consuming Co-CuxO Nanozyme for Starvation/Cuproptosis/Chemodynamic Synergistic Therapy.
Combining glucose oxidase (GOx) with peroxidase-like (POD) nanozymes is a well-established strategy for synergistic starvation and chemodynamic therapy (CDT). However, the low catalytic efficacy of most nanozymes compared to GOx often leads to wasteful accumulation of hydrogen peroxide (H2O2), which can inhibit GOx act...