Author

Qian Zhou

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Review Open access Aug 2026

RNA splicing in health and disease

This review describes how spliceosome assembly, splicing regulatory elements, splicing factors, epigenetic modifications, and post-transcriptional processes determine splice-site selection and suggests that safe clinical translation will require greater selectivity, reduced off-target toxicity, and preservation of esse...

Huining Huang, Yao Yu, Qian Zhou et al. · Molecular Biomedicine · 0 citations