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Author

Qiang Chen

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Open access Sep 2026

NPAS2 promotes MASLD and hepatocarcinogenesis through SIRT1-mediated PPARγ suppression

Emerging evidence links circadian disruption to metabolic dysfunction-associated steatotic liver disease (MASLD), but the underlying mechanisms remain elusive. NPAS2, a core circadian regulator, has an undefined role in the pathogenesis of MASLD and its progression to hepatocellular carcinoma (HCC). This study aime...

Jiao Mu, Jia-Li Ye, Jia-Hao Zhang et al. · 0 citations

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