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Qiang Guan

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Open access Sep 2026

A Hybrid Quantum–AI Framework for Protein Structure Prediction on NISQ Devices

Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid framework that combines quantum computation with deep learning, formulating str...

Yu-Qi Zhang, Yuxin Yang, Fei-Xiong Cheng et al. · 0 citations
Preprint Aug 2026

Q-MAP: Multi-Platform Benchmarking of Distributed Quantum Computing for Coherent Controlled Islanding

In this study, a round-synchronous distributed quantum computing framework is developed for coherent controlled islanding under a fixed per-circuit qubit budget and attains optimal and operationally feasible partitions on every platform under noise.

Yu-Qi Jiang, Zhi-Ding Liang, Qiang Guan et al. · 0 citations
Preprint Aug 2026

PACE-QAOA: Physics-Constrained Quantum Optimization for Qubit-Efficient Power System Islanding

A qubit-efficient hybrid quantum framework combining a physics-informed compact encoding with Lagrangian constraint handling and classical feasibility refinement is presented, offering a transferable approach for scaling constrained quantum optimization toward larger real-world applications on near-term hardware.

Yu-Qi Jiang, Zhi-Ding Liang, Qiang Guan et al. · 2 citations · ⚡1
Preprint Aug 2026

SPLIT-Q: A Scalable Sequential Quantum Computing Framework for Coherent Controlled Islanding

The proposed framework provides a feasible and scalable pathway for quantum optimization in large-scale power systems and substantially reduces quantum-resource demand and circuit complexity relative to monolithic QAOA, allowing large islanding problems to be addressed within current hardware limits.

Yu-Qi Jiang, Zhi-Ding Liang, Qiang Guan et al. · 0 citations
Preprint Jul 2026

Quantum Sampling Architecture for Protein Structure Reconstruction on Utility-Scale Hardware

QSAD is presented, a quantum-classical framework that reformulates peptide structure prediction as amino-acid-level Hamiltonian sampling and replaces iterative optimization with non-iterative Hamiltonian evolution and establishes coarse-grained quantum sampling as a practical computational path for structure prediction...

Yuqi Zhang, Bo Fang, Yuxin Yang et al. · 1 citation

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