Author

Qiang-Qiang Zheng

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Review Open access Aug 2026

Gut microbiota-regulated cell death: a review on pyroptosis, ferroptosis, and related mechanisms

The intestinal microbiota has emerged as a crucial regulator of host physiological functions, significantly influencing various forms of regulated cell death (RCD). Among these, pyroptosis and ferroptosis play pivotal roles in immune regulation, metabolic homeostasis, and disease progression. The gut microbiota modulat...

Yi Shen, Yun-Feng Zhou, Yang Yuan et al. · Frontiers in Microbiology · 0 citations

Review Open access Aug 2026

Decoding the molecular mechanisms of pyroptosis and its therapeutic development prospects

This review systematically summarizes the molecular regulatory mechanisms of pyroptosis, encompassing classical and non-classical inflammasome pathways, activation and modulation of gasdermin proteins, and the intricate signaling networks involved.

Yi Shen, Qiang-Qiang Zheng, Yang Yuan et al. · Frontiers in Cell and Develo... · 0 citations