Background Gastric cancer (GC) remains a leading cause of cancer-related mortality, with progression driven largely by the tumor microenvironment (TME). Tumor-associated macrophages (TAMs), the most abundant immune cells in the GC stroma, drive immune evasion, angiogenesis, metastasis, and chemoresistance through polar...
Xiaodong Zhuang, Qiang Yang, Liangjiu Huang et al.· Frontiers in Oncology· 0 citations
The oncogenic ELFN1-AS1/LYPLA1 regulatory cascade is characterized as a potential biomarker and therapeutic target for precision management of osteosarcoma and establishes an LMRL-based for osteosarcoma prognostic stratification that reflects immune, genomic and therapeutic heterogeneity.
Xian-Fu Wei, Zhi-Peng Wang, Qiang Yang et al.· Frontiers in Immunology· 0 citations
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