Integrative transcriptomic analysis identifies lactylation subtypes and a lactylation-related prognostic signature in acute myeloid leukemia
Lactylation-related gene expression is associated with molecular subtypes, immune contexture and outcome in AML and has independent prognostic value and reproduces, with modest effect sizes, in external cohorts; it is best regarded as a hypothesis-generating candidate biomarker for metabolism- and immune-directed resea...