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Open access Sep 2026

Amphotericin B-loaded polyphenolic nanoparticles for synchronous fungal eradication and immunomodulation in treating superficial fungal infections

Fungal infection represents an escalating global health threat, yet effective treatment remains clinically challenging due to the poor solubility, limited bioavailability, and pronounced cytotoxicity of conventional antifungal agents. To overcome these limitations, a self-assembled nanoparticle (ATE NPs) is developed b...

Yong-Nan Chen, Fu-Yao Chen, Shi-Ya Wang et al. · 0 citations
Open access Sep 2026

Biohybrid nanovesicle-mediated targeted delivery of HSP90 inhibitor for enhanced sorafenib therapy of hepatocellular carcinoma after radiofrequency ablation

Hepatocellular carcinoma (HCC) presents significant therapeutic challenges due to enhanced liver cancer stem cell (LCSC) stemness and sorafenib resistance after radiofrequency ablation (RFA). To address these limitations, biohybrid nanovesicles (hNVs) are prepared by fusing milk-derived exosomes with sorafenib-resistan...

Ang-Feng Jiang, Xian-Fei Zhou, Jin-Chao Zhao et al. · 0 citations

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