Qiaohua Zheng

Escalating demand for learning during adolescence impairs social interaction by hyperactivating midbrain dopamine neurons in young adulthood male mice.

Chronic stress during adolescence is a major risk factor for adult psychiatric disorders, yet the long-term impact of learning-related aversive stress remains poorly understood. This study established an mice model of learning demand stress by escalating the fixed ratio (FR) number of escape responses to foot shocks in...