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Open access Aug 2026

Real-world clinical characteristics of motor disorders for personalised brain-computer interfaces: phenotypic insights from a specialised clinic.

Motor dysfunction caused by neurological disorders such as stroke, spinal cord injury and amyotrophic lateral sclerosis has become a major global public health issue. Conventional rehabilitation approaches yield limited efficacy, highlighting the urgent need for innovative therapies. Brain-computer interface (BCI) tech...

Xiao-Ke Chai, Zhiyao Zheng, Nan Wang et al. · 0 citations
Review Open access Sep 2026

Neural Circuit Mechanisms of Disorders of Consciousness and Potential Therapeutic Targets of Brain Stimulation

ABSTRACT Background Disorders of consciousness (DoC) lack an integrated framework to guide neuromodulation. This review updates three hierarchical frameworks—ARAS, mesocircuit, and ICNs—and maps therapeutic targets within each. Methods We synthesized recent neuroanatomical, optogenetic, neuroimaging, and clinical trial...

Yi-Chen Zhou, Tian-Qing Cao, Si-Peng Zhu et al. · 0 citations

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