Author

Qin-Xin Zhang

3 papers indexed here

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Open access Sep 2026

The Multi-Omics Landscape of Enzymatic Alterations in Systemic Lupus Erythematosus.

OBJECTIVE Systemic lupus erythematosus (SLE) is an autoimmune disease closely associated with enzyme dysfunction, yet its underlying molecular mechanisms remain incompletely understood. This study aims to characterize enzyme-network alterations associated with SLE status and disease activity and to identify candidate m...

Ling-Ling Zhou, Qin-Xin Zhang, Wei Zhang et al. · PROTEOMICS - Clinical Applic... · 0 citations

Aug 2026

Development and validation of a generalizable M-protein screening model using routine laboratory indicators: a multicenter retrospective study.

BACKGROUND Early detection of plasma cell disorders (PCDs) remains challenging due to limited accessibility of gold standard diagnostic methods. This study aimed to develop a simple M-protein screening model using routine laboratory indicators for clinical laboratories. METHODS A total of 5217 participants from three...

Hou-Long Luo, Lan-Xin Zhou, Hua Xiao et al. · Clinica chimica acta; intern... · 0 citations

Open access Aug 2026

Integrated multi-omics profiling identifies aging-related molecular signatures and convergent interferon signaling in systemic lupus erythematosus

This integrative multi-omics study identifies inflammatory and interferon-dominated molecular alterations in SLE PBMCs that overlap with aging-related biological processes and converge on shared regulatory networks.

Hong-Wei Zeng, Donge Tang, Yong Dai et al. · Frontiers in Immunology · 0 citations