Pancreatic cancer is widely acknowledged as one of the most aggressive malignancies of the digestive system. More than 80% of patients are diagnosed at an advanced stage with an extremely poor prognosis. While contemporary combination chemotherapy and the novel RAS inhibitor daraxonrasib have modestly prolonged survi...
Shan-Shan Chen, Yun-Qing Xie, Shao-Hua Xu et al.· Frontiers in Immunology· 0 citations
Photothermal therapy (PTT) offers the advantages of noninvasiveness and high selectivity, while chemotherapy shows potent antitumor activity. However, their standalone applications are limited by insufficient photothermal ablation efficacy and chemotherapeutic resistance, respectively. To address these challenges, we...
Yu Jiang, Chen Guo, Zhen-Kun Sun et al.· Molecular Pharmaceutics· 0 citations
This work synthesized iRGD-functionalized DSPE-PEG2000-iRGD and pH-sensitive HA-g-DEAP polymers, and fabricated multifunctional M5/NMN/DEAP/iRGD-Lip liposomes via the thin-film dispersion method, which possess pH responsiveness and enhanced tumor-targeting ability.
Junwei Zhuang, Chen Guo, Xingming Ye et al.· Colloids and Surfaces B: Bio...· 0 citations
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