Zaoshi Huatan Xiefei formula improved severe pneumonia by regulating MAPK/NF-κB/VCAM1 signaling pathway mediated leukocyte transendothelial migration.
BACKGROUND Zaoshi Huatan Xiefei Formula (ZHXF) is a Chinese medicine prescription used in the treatment of severe pneumonia (SP). Although clinical studies have confirmed its efficacy in improving pneumonia, the specific bioactive components and their intricate regulatory pathwaysremain incompletely understood. PURPO...