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Qing-Fan Zeng

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Sep 2026

C21 ameliorates microglial ferroptosis and neuronal apoptosis after ischemic brain injury by activating the METTL3/USP18/FASN axis.

BACKGROUND Microglial ferroptosis is a key risk factor promoting neuroinflammation after ischemic brain injury (IBI). Although Compound 21 (C21) has neuroprotective and anti-inflammatory properties, its role in modulating microglial ferroptosis in IBI remains unexplored. METHODS IBI was induced in C57BL/6 mice via tr...

Yi-Jiu Wu, Xin-Qiang Zhou, Xu-Fang Huo et al. · 0 citations

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