Review
Open access
Oct 2026
Mosaic Loss of the Y Chromosome: Mechanisms and Diseases.
Mosaic loss of the Y chromosome (mLOY) is a male‑specific somatic loss of the Y chromosome that is predominantly observed in peripheral blood leukocytes, but can also be found in other tissue types. It represents one of the most common male-specific somatic mutations, particularly prevalent in aging individuals. Accumu...
Qi Zhang, Jiang Yu, X. Zhai et al.
· Protein & Cell · 0 citations