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Aug 2026

Cantharidin Causes Hepatotoxicity by Disrupting GSH-Mediated Redox Homeostasis.

Cantharidin (CTD) possesses potent anticancer activity, whereas its prominent hepatotoxicity severely limits its clinical application. Because the detailed molecular mechanisms responsible for CTD-triggered hepatotoxicity have not been fully elucidated, additional investigations are necessary to uncover its toxicologic...

Hong Tang, Qing Rao, Ting Liu et al. · 0 citations
Open access Aug 2026

Wogonoside alleviates metabolic dysfunction-associated steatohepatitis by modulating AMPK and xCT/GPX4 pathways to restrain lipid dysregulation and ferroptosis

Background Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive form of metabolic dysfunction-associated steatotic liver disease with limited pharmacological treatment options. Wogonoside (WOG), a flavonoid isolated from Scutellaria baicalensis, exhibits anti-inflammatory, antioxidant, and lipid-low...

Daoping Wang, Yu Mou, Xue-Mei Wu et al. · 0 citations

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