Open access
Oct 2026
m7G modification in mRNA cooperates with QKI to promote homologous recombination repair.
DNA double strand breaks (DSBs) are repaired through distinct pathways, with homologous recombination (HR) favored when DNA ends undergo extensive resection. Although cytoplasmic N7-methylguanosine (m7G)-modified RNA increases after UV-induced single-strand breaks, its role in DSB repair (including HR) remains unclear....
Xin-Yun Chen, Meng-Yan Li, Zhi-Chao Liu et al.
· Proceedings of the National... · 0 citations