Author

Qing-Sheng Qi

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Open access Aug 2026

Dynamic Control of Prokaryotic Chromosome Ploidy Rewires Metabolic Networks to Enhance Product Biosynthesis

Building high-performance microbial cell factories requires dynamic coordination of resource allocation among cellular growth, target-product biosynthesis, and endogenous host metabolism. However, existing polyploid engineering strategies rely primarily on static manipulation of chromosome copy number. Although increas...

Xin Jin, Yaping Gao, Hannuo Shen et al. · bioRxiv · 0 citations

Open access Sep 2026

Additive-Assisted Consolidated Bioprocessing of Untreated Desert Willow (Salix psammophila) for Bioethanol Production by a Thermophilic Co-Culture

Consolidated bioprocessing (CBP) using Acetivibrio thermocellus offers a promising route for the direct conversion of recalcitrant lignocellulose into ethanol. In this study, a synergistic co-culture system comprising A. thermocellus C1 and Thermoanaerobacterium thermosaccharolyticum DSM571 was established for the bioc...

Jin-Na Cui, Bo-Han Wang, Qing-Sheng Qi et al. · Processes · 0 citations

Jul 2026

Engineering 2,4-Diacetylphloroglucinol-Hyper-Tolerant Escherichia coli via Adaptive Evolution for Efficient Biosynthesis and an Organic Solvent-Free Downstream Process.

2,4-Diacetylphloroglucinol (DAPG) is a valuable antimicrobial compound with significant agricultural potential, suffers bioproduction limitations from host toxicity and inefficient downstream processing. This study engineered DAPG-hyper-tolerant Escherichia coli via adaptive laboratory evolution (ALE) starting from a p...

Jingnan Wang, Mingyu Liu, Cheng Li et al. · ACS Synthetic Biology · 0 citations