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Qing-Tao Meng

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Open access Jul 2026

Hippocampal mediation in the lipid–Alzheimer's disease pathway: A high‐dimensional mediation analysis stratified by APOE and sex

The left hippocampus is a critical mediator linking specific plasma lipids to AD progression, with an additional vascular pathway via white matter hyperintensities emerging after comorbidity adjustment, supporting a dual neurodegenerative–vascular pathway.

Yun-Jia Cao, Yu-Wei Fan, Qing-Tao Meng et al. · Alzheimer's & Dementia · 0 citations