ABSTRACT Glioblastoma (GBM) is a lethal malignancy characterized by therapeutic resistance and recurrence, which are driven by dynamic cellular metabolic adaptation within the tumor microenvironment. However, the precise molecular metabolic mechanisms remain poorly understood. Here, we found that palmitic acid (PA) acc...
Zi-Jie Gao, Rong-Rong Zhao, Zhe-Yuan Chen et al.· Advancement of science· 0 citations
Molecularly informed maximal safe resection of diffuse glioma requires rapid assessment of surgical specimens, but conventional molecular assays are not suited to repeated ex vivo testing. We developed a deep learning-assisted terahertz (THz) metasurface workflow in which a K/I-patterned aluminum metasurface both serve...
Chuan-Zheng Wang, Qing-Tong Wang, Lu Liu et al.· ACS Sensors· 0 citations
Tumor Electric Field Therapy (TEFT) disrupts mitosis in glioblastoma (GBM), but responses vary markedly among patients. In a retrospective cohort of TEFT-treated GBM, EGFR variant III (EGFRvIII) alteration is associated with shorter progression-free survival, prompting us to investigate a genotype-linked resistance mec...