Open access
Aug 2026
maA dual-target modulator of STK11 and PP2Acα from the flowers of Chrysanthemum indicum mitigates drug-induced liver injury.
Novel guaianolide sesquiterpenoid CI was identified as an affinity-dependent dual-target regulator of STK11 and PP2Ac α with low affinity to inhibit AMPK activation to alleviate DILI.
Fei Zhou, Yu Liu, Haoyu Zhao et al.
· Journal of Advanced Research · 0 citations