Qing-Yang Li

Chlorpyrifos and its metabolite 3,5,6-trichloro-2-pyridinol elicit MASLD-related lipid metabolic perturbations in HepG2 cells.

Metabolic dysfunction-associated steatotic liver disease (MASLD) has been increasingly linked to environmental chemical exposure, yet the metabolic consequences of pesticide parent-metabolite co-exposure remain poorly understood. HepG2 cells were exposed for 48 h to chlorpyrifos (CPF, 10 mg/L), its major metabolite 3,5...