Open access
Sep 2026
HOTAIR regulates osteogenic–adipogenic differentiation imbalance through the miR-217/DKK1-mediated Wnt/β-catenin pathway in SONFH-BMSCs
Steroid-induced osteonecrosis of the femoral head (SONFH) is characterized by disrupted osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). The long noncoding RNA HOTAIR is aberrantly upregulated in SONFH-BMSCs, yet its functional role in the differentiation imbalance remains in...
Min Yi, Fei-Fei Lin, Zhen-Wu Du et al.
· Frontiers in Genetics · 0 citations