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Qing-Zhang Tuo

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Open access Aug 2026

Poly (Lipoic Acid) Nanoparticles With High Blood-Brain Barrier Permeability and Enhanced Anti-Ferroptotic Activity for Ischemic Stroke Treatment.

Lipoic acid (LA) scavenges free radicals and was clinically tested for ischemic stroke. However, the short half-life and weak efficacy in penetrating the blood-brain barrier (BBB) limit its use in the brain. Here, we developed poly (lipoic acid) nanoparticles (pLANs) with a half-life of more than 15 h and a high effici...

Qing-Zhang Tuo, Juan Tan, Hong-Fa Yan et al. · 0 citations

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