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Qingyun Li

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Review Open access Aug 2026

Role of STX1A in Parkinson’s disease: evidence, mechanistic hypotheses, and translational perspectives

The biomarker and therapeutic potential of STX1A remains preliminary because diagnostic performance, disease specificity, longitudinal stability, and causal relevance have not been adequately validated and future studies using cell-type-specific STX1A manipulation, rescue experiments, electrophysiology, and multicenter longitudinal cohorts are required to define the biological and clinical significance of STX1A in PD.

Rui Xu, Rui Li, Hongmei Li et al. · 0 citations