Open access
Aug 2026
Preliminary transcriptome profiling of induced pluripotent stem cell-derived hematopoietic stem and progenitor cells in Kawasaki disease
iPSC-derived HSPCs from patients with KD display altered immune-inflammatory transcriptional profiles and suppressed B-cell developmental signatures at the transcriptomic level, which suggest that early hematopoietic immune dysregulation may contribute to KD pathogenesis.
Lian-Ni Mei, Lei Gao, Rui-Zhi Zhang et al.
· Frontiers in Pediatrics · 0 citations